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2. Enter the peptide sequence using the universal one-letter code. Determine the type of amino- and carboxyl-terminus ends you need by checking the correct box below the peptide sequence.
| Alanine |
Ala (A) |
Histidine |
His (H) |
Proglutamic Acid |
pGlu |
| Arginine |
Arg (R) |
Homocysteine |
Hcy |
Phenylalanine |
Phe (F) |
| Asparagine |
Asn (N) |
Homoserine |
Hse |
Proline |
Pro (P) |
| Aspartic acid |
Asp (D) |
Hydroxyproline |
Hyp |
Pyroglutamic acid |
Pyr |
| Aminosuberic Acid |
Asu |
Isoleucine |
Ile (I) |
Serine |
Ser (S) |
| Chloromethylketone |
CMK |
Leucine |
Leu (L) |
Statine |
Sta |
| Cyclohexyl |
Chx |
Lysine |
Lys (K) |
Threonine |
Thr (T) |
| Cysteine |
Cys (C) |
Methionine |
Me t(M) |
B-[2-Thienyl]Alanine |
Thi |
| Cystine |
(Cys)2 |
Norleucine |
Nle |
Sarcosine |
Sar |
| Glutamic Acid |
Glu (E) |
Norvaline |
Nva |
Tryptophan |
Trp(W) |
| Glutamine |
Gln (Q) |
Ornithine |
Om (O) |
Tyrosine |
Tyr(Y) |
| Glycine |
Gly (G) |
Pencillamine |
Pen |
Valine |
Val(V) |
| Adamantaneacetyl |
Aaa |
1-Hydroxybenzotriazole |
Hobt |
2-Nitrophenylsulfonyl |
Nps |
| (-Aminobutyric Acid |
Abu |
N-Hydroxysuccinimide |
Hosu |
3-Nitro-2-Pyridinesulfonyl |
Npys |
| 2-Aminobenzoyl |
Abz |
Isopropyl |
ipr |
Benzyl Ester |
OBzl |
| Acetyl |
Ac |
Methylbenzhydrylamine |
MBHA |
Cyclohexyl Ester |
OChx |
| Aminocaproic |
Aca |
4-Methoxybenzyl |
Mbzl |
Ethyl Ester |
OEt |
| Acetamidomethyl |
Acm |
4-methyl-Coumaryl-7-Acetyl |
MCA |
Methyl Ester |
OMe |
| 6-Aminohexanic Acid |
C6 |
Methyl |
Me |
Dicyclohexylammoniumsalt |
DCHA |
| (-Aminosobutyric Acid |
Aib |
Succinyl |
Su |
2,4,-Dinitrophenyl |
DNP |
| 7-Amino-4-Methylcoumarin |
AMC |
2-(1H-Benzotrialzole-1-yl)1,1,3,3-Tetramethyluronium Tetrafluoroborate |
TBTU |
t-Butyl Ester |
OtBu |
| Benzhydrylamine |
BHA |
4-Toluenesulfonyl |
Tos |
4-methylbenzyl |
p-MeBzl |
| t-Butyloxycarbonyl |
Boc/t-Boc |
Xanthyl |
Xan |
Phenylacetamidomethyl |
PAM |
| Benzyloxymethyl |
Bom |
3-(4-Methylbenyl)-Thiopropionic Acid |
Mpr |
Phenylglycine |
Phg |
| (Castro's reagent) Benxotriazolyl-N-Oyl-tris (Dimethylamino)Phosphonium Hexafluorophosphate |
BOP |
4-Methoxy-2,3,6-Trimethylbenzeneculfonyl |
Mtr |
2,2,5,7,8-Pentamethylchroman-6-sulfonyl |
Pmc |
| 2-p-Biphenylisopropyloxycarbonyl |
Bpoc |
Mesitylene--2-sulfonyl |
Mts |
beta-Mercapto-b,b-cyclopentamethylene Propionic Acid |
Pmp |
| Benzoyl |
Bz |
Guanidine Nitrogen |
N-g |
p_Nitroanilide |
pNA |
| Benzyl |
Bzl |
Imidazole Nitrogen |
N-im |
Sarcosine |
Sar |
| Benzyloxycarbonyl |
Cbz,Z |
Indole Nitrogen |
N-in |
Statine |
Sta |
| Dicyclohexylcarbodiimide |
DCC |
N-Ethylamide |
N-im |
t-Butylthio |
StBu |
| 2,4-Dimethyloxybenxyl |
Dmob |
Hydrazide |
NHNH2 |
t-Butyl |
t-Bu |
| 9-Fluorenylmethyloxycarbonyl |
Fmoc |
N-MethylamideM |
NMe |
Trifluoroacetyl |
tfa |
| Formyl |
For |
N,N-Dimethylamide |
NMe2 |
Trithyl |
Trt |
| 2-(1H-Benzotriazol-1-yl)-1,1,3,3-Tetramethyluronium Hexafluorophosphate |
HBTU |
Nitro |
NO2 |
Benzyloxycarbonyl |
Z/Cbz |
Modifications
Phosphorylation: B=pSer, J=pTyr, U=pThr, use this code in the peptide sequence
Methylation: X=methyl-Arg, Z=methyl-Lys, use this code in the peptide sequence
Conjugation:
KLH
BSA
Versa
other:
Cyclic peptide
Other:
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